{"id":310,"date":"2021-04-13T17:15:36","date_gmt":"2021-04-13T09:15:36","guid":{"rendered":"http:\/\/www.wayln.com\/?p=310"},"modified":"2021-04-15T09:49:39","modified_gmt":"2021-04-15T01:49:39","slug":"%e8%a7%a3%e8%af%bb%e5%85%89%e5%ad%a6%e7%9b%b8%e5%b9%b2%e5%b1%82%e6%9e%90oct%e6%88%90%e5%83%8f%e6%8a%80%e6%9c%af","status":"publish","type":"post","link":"https:\/\/www.wayln.com\/?p=310","title":{"rendered":"\u89e3\u8bfb\u5149\u5b66\u76f8\u5e72\u5c42\u6790(OCT)\u6210\u50cf\u6280\u672f"},"content":{"rendered":"

\u5149\u5b66\u76f8\u5e72\u5c42\u6790(Optical Coherence Tomography\uff0c\u7b80\u79f0 OCT)\u662f 20 \u4e16\u7eaa 90 \u5e74\u4ee3\u521d\u53d1\u5c55\u8d77\u6765\u7684\u4f4e\u635f\u3001\u9ad8\u5206\u8fa8\u3001\u975e\u4fb5\u5165\u5f0f\u7684\u533b\u5b66\u3001\u6210\u50cf\u6280\u672f\u3002\u5b83\u7684\u539f\u7406\u7c7b\u4f3c\u4e8e\u8d85\u58f0\u6210\u50cf\uff0c\u4e0d\u540c\u4e4b\u5904\u662f\u5b83\u5229\u7528\u7684\u662f\u5149\uff0c\u800c\u4e0d\u662f\u58f0\u97f3\u3002
\n\"\"<\/a><\/p>\n

\u5149\u5b66\u76f8\u5e72\u5c42\u6790\u6280\u672f\u5b83\u5229\u7528\u5f31\u76f8\u5e72\u5149\u5e72\u6d89\u4eea\u7684\u57fa\u672c\u539f\u7406\uff0c\u68c0\u6d4b\u751f\u7269\u7ec4\u7ec7\u4e0d\u540c\u6df1\u5ea6\u5c42\u9762\u5bf9\u5165\u5c04\u5f31\u76f8\u5e72\u5149\u7684\u80cc\u5411\u53cd\u5c04\u6216\u51e0\u6b21\u6563\u5c04\u4fe1\u53f7\uff0c\u901a\u8fc7\u626b\u63cf\uff0c\u53ef\u5f97\u5230\u751f\u7269\u7ec4\u7ec7\u4e8c\u7ef4\u6216\u4e09\u7ef4\u7ed3\u6784\u56fe\u50cf\u3002<\/p>\n

\u76f8\u6bd4\u5176\u5b83\u4e00\u4e9b\u6210\u50cf\u6280\u672f\uff0c\u4f8b\u5982\u8d85\u58f0\u6210\u50cf\u3001\u6838\u78c1\u5171\u632f\u6210\u50cf(MRI)\u3001X-\u5c04\u7ebf\u8ba1\u7b97\u673a\u65ad\u5c42(CT)\u7b49\uff0cOCT \u6280\u672f\u5177\u5907\u4e0e\u4e4b\u76f8\u6bd4\u8f83\u9ad8\u7684\u5206\u8fa8\u7387(\u51e0\u5fae\u7c73\u7ea7)\uff0c\u540c\u65f6\uff0c\u4e0e\u5171\u805a\u7126\u663e\u5fae(\u3001\u591a\u5149\u5b50\u663e\u5fae\u6280\u672f\u7b49\u8d85\u9ad8\u5206\u8fa8\u6280\u672f\u76f8\u6bd4\uff0cOCT \u6280\u672f\u53c8\u5177\u6709\u4e0e\u4e4b\u76f8\u6bd4\u8f83\u5927\u7684\u5c42\u6790\u80fd\u529b\u3002\u53ef\u4ee5\u8bf4 OCT \u6280\u672f\u586b\u8865\u4e86\u8fd9\u4e24\u7c7b\u6210\u50cf\u6280\u672f\u4e4b\u95f4\u7684\u7a7a\u767d\u3002<\/p>\n

\u5149\u5b66\u76f8\u5e72\u5c42\u6790\u6210\u50cf\u7684\u7ed3\u6784\u53ca\u57fa\u672c\u539f\u7406
\n\"\"<\/a><\/p>\n

\u5149\u5b66\u76f8\u5e72\u5c42\u6790\u6210\u50cf\u57fa\u4e8e\u5e72\u6d89\u4eea\u539f\u7406\uff0c\u5229\u7528\u8fd1\u7ea2\u5916\u5f31\u76f8\u5e72\u5149\u7167\u5c04\u5230\u5f85\u6d4b\u7ec4\u7ec7\uff0c\u4f9d\u636e\u5149\u7684\u76f8\u5e72\u6027\u4ea7\u751f\u5e72\u6d89\uff0c\u91c7\u7528\u8d85\u5916\u5dee\u63a2\u6d4b\u6280\u672f\uff0c\u6d4b\u91cf\u53cd\u5c04\u56de\u6765\u7684\u5149\u5f3a\uff0c\u7528\u4e8e\u7ec4\u7ec7\u6d45\u8868\u5c42\u6210\u50cf\u3002OCT \u7cfb\u7edf\u662f\u7531\u4f4e\u76f8\u5e72\u5149\u6e90\u3001\u5149\u7ea4\u8fc8\u514b\u5c14\u900a\u5e72\u6d89\u4eea\u548c\u5149\u7535\u63a2\u6d4b\u7cfb\u7edf\u7b49\u6784\u6210\u3002
\n\"\"<\/a><\/p>\n

OCT\u7684\u6838\u5fc3\u662f\u5149\u7ea4\u8fc8\u514b\u5c14\u900a\u5e72\u6d89\u4eea\u3002\u4f4e\u76f8\u5e72\u5149\u6e90\u8d85\u8f90\u5c04\u53d1\u5149\u4e8c\u6781\u7ba1(Superluminescence Diode\uff0cSLD)\u53d1\u51fa\u7684\u5149\u8026\u5408\u8fdb\u5165\u5355\u6a21\u5149\u7ea4\uff0c\u88ab2\u00d72\u5149\u7ea4\u8026\u5408\u5668\u5747\u5206\u4e3a\u4e24\u8def\uff0c\u4e00\u8def\u662f\u7ecf\u900f\u955c\u51c6\u76f4\u5e76\u4ece\u5e73\u9762\u53cd\u5c04\u955c\u8fd4\u56de\u7684\u53c2\u8003\u5149;\u53e6\u4e00\u8def\u662f\u7ecf\u900f\u955c\u805a\u7126\u5230\u88ab\u6d4b\u6837\u54c1\u7684\u91c7\u6837\u5149\u675f\u3002<\/p>\n

\u7531\u53cd\u5c04\u955c\u8fd4\u56de\u7684\u53c2\u8003\u5149\u4e0e\u88ab\u6d4b\u6837\u54c1\u7684\u540e\u5411\u6563\u5c04\u5149\u5728\u63a2\u6d4b\u5668\u4e0a\u6c47\u5408\uff0c\u5f53\u4e24\u8005\u4e4b\u95f4\u7684\u5149\u7a0b\u5dee\u5728\u5149\u6e90\u76f8\u5e72\u957f\u5ea6\u4e4b\u5185\u65f6\u5219\u53d1\u751f\u5e72\u6d89\uff0c\u63a2\u6d4b\u5668\u8f93\u51fa\u4fe1\u53f7\u53cd\u6620\u4ecb\u8d28\u7684\u540e\u5411\u6563\u5c04\u5f3a\u5ea6\u3002<\/p>\n

\u626b\u63cf\u53cd\u5c04\u955c\u5e76\u8bb0\u5f55\u5176\u7a7a\u95f4\u4f4d\u7f6e\uff0c\u4f7f\u53c2\u8003\u5149\u4e0e\u6765\u81ea\u4ecb\u8d28\u5185\u4e0d\u540c\u6df1\u5ea6\u7684\u540e\u5411\u6563\u5c04\u5149\u53d1\u751f\u5e72\u6d89\u3002\u6839\u636e\u53cd\u5c04\u955c\u4f4d\u7f6e\u548c\u76f8\u5e94\u7684\u5e72\u6d89\u4fe1\u53f7\u5f3a\u5ea6\u5373\u753a\u83b7\u5f97\u6837\u54c1\u4e0d\u540c\u6df1\u5ea6(z\u65b9\u5411)\u7684\u6d4b\u91cf\u6570\u636e.\u518d\u7ed3\u5408\u91c7\u6837\u5149\u675f\u5728x-y\u5e73\u9762\u5185\u7684\u626b\u63cf\uff0c\u6240\u5f97\u7ed3\u679c\u7ecf\u8ba1\u7b97\u673a\u5904\u7406\uff0c\u53ef\u83b7\u5f97\u6837\u54c1\u7684\u4e09\u7ef4\u7ed3\u6784\u4fe1\u606f\u3002<\/p>\n

OCT\u6210\u50cf\u6280\u672f\u7684\u53d1\u5c55<\/p>\n

\u968f\u7740\u8d85\u58f0\u6ce2\u68c0\u67e5\u5728\u773c\u79d1\u9886\u57df\u7684\u5e7f\u6cdb\u5e94\u7528\uff0c\u4eba\u4eec\u5e0c\u671b\u53d1\u5c55\u4e00\u79cd\u66f4\u9ad8\u5206\u8fa8\u7387\u7684\u68c0\u6d4b\u624b\u6bb5\u3002\u8d85\u58f0\u751f\u7269\u663e\u5fae\u955c(UBM)\u7684\u51fa\u73b0\u5728\u4e00\u5b9a\u7a0b\u5ea6\u4e0a\u6ee1\u8db3\u4e86\u8fd9\u4e00\u8981\u6c42\uff0c\u5b83\u901a\u8fc7\u4f7f\u7528\u66f4\u9ad8\u9891\u7387\u7684\u58f0\u6ce2\uff0c\u53ef\u4ee5\u5bf9\u773c\u524d\u6bb5\u8fdb\u884c\u9ad8\u5206\u8fa8\u7387\u7684\u6210\u50cf\u3002\u4f46\u662f\u7531\u4e8e\u9ad8\u9891\u7387\u58f0\u6ce2\u5728\u751f\u7269\u7ec4\u7ec7\u5185\u8fc5\u901f\u8870\u51cf\uff0c\u5b83\u5728\u7684\u63a2\u6d4b\u6df1\u5ea6\u53d7\u5230\u4e00\u5b9a\u7684\u9650\u5236\u3002\u5982\u679c\u7528\u5149\u6ce2\u4ee3\u66ff\u58f0\u6ce2\uff0c\u5176\u7f3a\u9677\u662f\u5426\u53ef\u4ee5\u5f97\u5230\u8865\u507f\u5462?<\/p>\n

1987\u5e74\uff0cTakada\u7b49\u7814\u7a76\u51fa\u5149\u5b66\u7684\u4f4e\u76f8\u5e72\u5e72\u6d89\u6d4b\u91cf\u6cd5\uff0c\u5b83\u662f\u5728\u7ea4\u7ef4\u5149\u5b66\u548c\u5149\u7535\u7ec4\u4ef6\u7684\u652f\u6301\u4e0b\u53d1\u5c55\u6210\u4e3a\u8fdb\u884c\u9ad8\u5206\u8fa8\u7387\u5149\u5b66\u6d4b\u91cf\u7684\u65b9\u6cd5;Youngquist\u7b49\u5219\u7814\u7a76\u51fa\u5149\u5b66\u76f8\u5e72\u53cd\u5c04\u8ba1\uff0c\u5176\u5149\u6e90\u662f\u4e00\u4e2a\u76f4\u63a5\u4e0e\u5149\u7ea4\u8026\u8054\u7684\u8d85\u7ea7\u53d1\u5149\u4e8c\u6781\u7ba1\uff0c\u4eea\u5668\u4e2d\u542b\u6709\u53c2\u8003\u955c\u9762\u7684\u4e00\u4e2a\u81c2\u4f4d\u4e8e\u5185\u90e8\uff0c\u800c\u53e6\u4e00\u4e2a\u81c2\u4e2d\u7684\u5149\u7ea4\u5219\u4e0e\u7c7b\u4f3c\u4e8e\u7167\u76f8\u673a\u7684\u8bbe\u5907\u76f8\u8fde\u63a5\u3002\u8fd9\u4e9b\u90fd\u4e3aOCT\u7684\u51fa\u73b0\u5960\u5b9a\u4e86\u7406\u8bba\u548c\u6280\u672f\u4f9d\u636e\u3002
\n\"\"<\/a><\/p>\n

1991\u5e74\uff0c\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u534e\u88d4\u79d1\u5b66\u5bb6David Huang\u7b49\u5c06\u7814\u5236\u7684OCT\u7528\u4e8e\u6d4b\u91cf\u79bb\u4f53\u7684\u89c6\u7f51\u819c\u548c\u51a0\u72b6\u52a8\u8109\u3002\u7531\u4e8eOCT\u5177\u6709\u524d\u6240\u672a\u6709\u7684\u9ad8\u5206\u8fa8\u7387\uff0c\u7c7b\u4f3c\u4e8e\u5149\u5b66\u6d3b\u68c0\uff0c\u56e0\u6b64\u5f88\u5feb\u5c31\u88ab\u53d1\u5c55\u7528\u4e8e\u751f\u7269\u7ec4\u7ec7\u7684\u6d4b\u91cf\u548c\u6210\u50cf\u3002<\/p>\n

\u7531\u4e8e\u773c\u90e8\u7684\u5149\u5b66\u7279\u70b9\uff0cOCT\u6280\u672f\u5728\u773c\u79d1\u4e34\u5e8a\u5e94\u7528\u53d1\u5c55\u5f97\u6700\u5feb\u30021995\u5e74\u4ee5\u524d\uff0cHuang\u7b49\u79d1\u5b66\u5bb6\u8fd0\u7528OCT\u5bf9\u79bb\u4f53\u53ca\u6d3b\u4f53\u4eba\u773c\u7684\u89c6\u7f51\u819c\u3001\u89d2\u819c\u3001\u524d\u623f\u53ca\u8679\u819c\u7b49\u7ec4\u7ec7\u8fdb\u884c\u6d4b\u91cf\u548c\u6210\u50cf\uff0c\u4e0d\u65ad\u5b8c\u5584OCT\u6280\u672f\u3002\u7ecf\u8fc7\u51e0\u5e74\u7684\u6539\u8fdb\uff0cOCT\u7cfb\u7edf\u8fdb\u4e00\u6b65\u5b8c\u5584\uff0c\u5e76\u53d1\u5c55\u6210\u4e3a\u4e00\u79cd\u4e34\u5e8a\u5b9e\u7528\u7684\u68c0\u6d4b\u5de5\u5177\uff0c\u5236\u6210\u4e86\u5546\u54c1\u5316\u4eea\u5668\uff0c\u5e76\u6700\u7ec8\u786e\u5b9a\u4e86\u5b83\u5728\u773c\u5e95\u53ca\u89c6\u7f51\u819c\u6210\u50cf\u65b9\u9762\u7684\u4f18\u8d8a\u6027\u30021995\u5e74OCT\u5f00\u59cb\u6b63\u5f0f\u7528\u4e8e\u773c\u79d1\u4e34\u5e8a\u3002<\/p>\n

1997\u5e74\uff0cOCT\u9010\u6e10\u88ab\u5e94\u7528\u4e8e\u76ae\u80a4\u79d1\u3001\u6d88\u5316\u9053\u3001\u6ccc\u5c3f\u7cfb\u7edf\u548c\u5fc3\u8840\u7ba1\u65b9\u9762\u7684\u68c0\u67e5\u3002\u98df\u7ba1\u3001\u80c3\u80a0\u3001\u6ccc\u5c3f\u7cfbOCT\u548c\u5fc3\u8840\u7ba1OCT\u5747\u4e3a\u4fb5\u5165\u6027\u68c0\u67e5\uff0c\u7c7b\u4f3c\u4e8e\u5185\u7aa5\u955c\u548c\u5bfc\u7ba1\uff0c\u4f46\u5b83\u7684\u5206\u8fa8\u7387\u66f4\u9ad8\uff0c\u53ef\u89c2\u5bdf\u8d85\u5fae\u7ed3\u6784\u3002\u76ae\u80a4OCT\u4e3a\u63a5\u89e6\u6027\u68c0\u67e5\uff0c\u4e5f\u53ef\u89c2\u5bdf\u8d85\u5fae\u7ed3\u6784\u3002<\/p>\n

\u6700\u521d\u5e94\u7528\u4e8e\u4e34\u5e8a\u7684OCT\u4e3aOCT1\uff0c\u5206\u522b\u7531\u63a7\u5236\u53f0\u548c\u52a8\u529b\u53f0\u7ec4\u6210\u3002\u63a7\u5236\u53f0\u5305\u62ecOCT\u8ba1\u7b97\u673a\u3001OCT\u663e\u793a\u5668\u3001\u63a7\u5236\u677f\u548c\u76d1\u89c6\u5c4f;\u52a8\u529b\u53f0\u5305\u62ec\u773c\u5e95\u89c2\u5bdf\u7cfb\u7edf\u3001\u5e72\u6d89\u5149\u63a7\u5236\u7cfb\u7edf\u3002\u7531\u4e8e\u63a7\u5236\u53f0\u548c\u52a8\u529b\u53f0\u4e3a\u76f8\u5bf9\u72ec\u7acb\u7684\u88c5\u7f6e\uff0c\u4e24\u8005\u4e4b\u95f4\u7531\u5bfc\u7ebf\u76f8\u8fde\uff0c\u6240\u4ee5\u4eea\u5668\u4f53\u79ef\u8f83\u5927\uff0c\u6240\u5360\u7a7a\u95f4\u8f83\u5927\u3002<\/p>\n

OCT1\u7684\u5206\u6790\u7a0b\u5e8f\u5206\u4e3a\u56fe\u50cf\u5904\u7406\u548c\u56fe\u50cf\u6d4b\u91cf\u3002\u56fe\u50cf\u5904\u7406\u5305\u62ec\u56fe\u50cf\u6807\u51c6\u5316\u3001\u56fe\u50cf\u6821\u51c6\u3001\u56fe\u50cf\u6821\u51c6\u4e0e\u6807\u51c6\u5316\u3001\u56fe\u50cf\u9ad8\u65af\u5e73\u6ed1\u3001\u56fe\u50cf\u4e2d\u503c\u5e73\u6ed1;\u56fe\u50cf\u6d4b\u91cf\u7a0b\u5e8f\u8f83\u5c11\uff0c\u53ea\u6709\u89c6\u7f51\u819c\u539a\u5ea6\u6d4b\u91cf\u4e0e\u89c6\u7f51\u819c\u795e\u7ecf\u7ea4\u7ef4\u5c42\u539a\u5ea6\u6d4b\u91cf\u3002\u4f46\u7531\u4e8eOCT1\u7684\u626b\u63cf\u7a0b\u5e8f\u53ca\u5206\u6790\u7a0b\u5e8f\u5747\u8f83\u5c11\uff0c\u56e0\u800c\u5f88\u5feb\u88abOCT2\u6240\u53d6\u4ee3\u3002<\/p>\n

OCT2\u662f\u5728OCT1\u7684\u57fa\u7840\u4e0a\u8fdb\u884c\u8f6f\u4ef6\u5347\u7ea7\u5f62\u6210\u3002\u4e5f\u6709\u4e00\u4e9b\u4eea\u5668\u662f\u5c06\u63a7\u5236\u53f0\u548c\u52a8\u529b\u53f0\u5408\u4e8c\u4e3a\u4e00\uff0c\u5f62\u6210OCT2\u7684\u4eea\u5668\uff0c\u8fd9\u79cd\u4eea\u5668\u51cf\u5c11\u4e86\u56fe\u50cf\u76d1\u89c6\u5668\uff0c\u5728\u540c\u4e00\u4e2a\u7535\u8111\u8367\u5c4f\u4e0a\u89c2\u5bdfOCT\u56fe\u50cf\u548c\u76d1\u89c6\u60a3\u8005\u7684\u626b\u63cf\u90e8\u4f4d\u60c5\u51b5\uff0c\u4f46\u64cd\u4f5c\u4e0eOCT1\u76f8\u4f3c\uff0c\u662f\u5728\u63a7\u5236\u677f\u4e0a\u624b\u52a8\u64cd\u4f5c\u3002<\/p>\n

2002\u5e74OCT3\u7684\u51fa\u73b0\uff0c\u6807\u5fd7\u7740OCT\u6280\u672f\u8fdb\u5165\u4e00\u4e2a\u65b0\u7684\u9636\u6bb5\u3002OCT3\u9664\u64cd\u4f5c\u754c\u9762\u66f4\u53cb\u597d\uff0c\u5168\u90e8\u64cd\u4f5c\u90fd\u53ef\u7528\u9f20\u6807\u5728\u7535\u8111\u4e0a\u5b8c\u6210\u5916\uff0c\u5176\u626b\u63cf\u548c\u5206\u6790\u7a0b\u5e8f\u65e5\u8d8b\u5b8c\u5584\u3002\u66f4\u91cd\u8981\u7684\u662f\uff0cOCT3\u7684\u5206\u8fa8\u7387\u66f4\u9ad8\u4e86\uff0c\u5176\u8f74\u5411\u5206\u8fa8\u7387\u226410 \u03bcm\uff0c\u6a2a\u5411\u5206\u8fa8\u7387\u4e3a20\u03bcm\u3002OCT3\u83b7\u53d6\u7684\u8f74\u5411\u6837\u672c\u4ece\u539f\u6765\u76841\u4e2aA\u626b\u63cf\u7684128\u4e2a\u589e\u52a0\u5230768\u4e2a\uff0c\u56e0\u6b64OCT3\u7684\u79ef\u5206\u4ece\u539f\u6765\u7684131 072\u4e2a\u589e\u52a0\u5230786 432\u4e2a\uff0c\u6784\u5efa\u7684\u626b\u63cf\u7ec4\u7ec7\u6a2a\u622a\u9762\u56fe\u50cf\u7684\u5c42\u6b21\u7ed3\u6784\u66f4\u6e05\u6670\u3002<\/p>\n

OCT\u6210\u50cf\u7684\u6280\u672f\u79cd\u7c7b<\/p>\n

OCT \u6280\u672f\u624b\u6bb5\u65b9\u9762\uff0c\u6839\u636e\u63a2\u6d4b\u4fe1\u53f7\u7684\u7c7b\u578b\u4e0d\u540c\uff0cOCT \u4e3b\u8981\u6709\u4e24\u79cd\u6280\u672f\u624b\u6bb5\uff1a\u65f6\u57df OCT(Time Domain OCT\uff0cTD-OCT)\u548c\u9891\u57df OCT(Fourier Domain OCT\uff0c FD-OCT)\u3002<\/p>\n

\u65f6\u57dfOCT\u6280\u672f<\/p>\n

\u65f6\u57dfOCT\u6280\u672f\u539f\u7406\u56fe\u5982\u4e0b\uff1a
\n\"\"<\/a><\/p>\n

\u5149\u5b66\u76f8\u5e72\u5c42\u6790\u6210\u50cf\u7cfb\u7edf\u7ed3\u5408\u4e86\u4f4e\u76f8\u5e72\u5e72\u6d89\u548c\u5171\u7126\u663e\u5fae\u6d4b\u91cf\u7684\u7279\u70b9\u3002\u7cfb\u7edf\u9009\u7528\u7684\u5149\u6e90\u4e3a\u5bbd\u5e26\u5149\u6e90\uff0c\u5e38\u7528\u7684\u662f\u8d85\u8f90\u5c04\u53d1\u5149\u4e8c\u6781\u7ba1(SLD)\u3002\u5149\u6e90\u53d1\u51fa\u7684\u5149\u7ecf2\u00d72\u8026\u5408\u5668\u5206\u522b\u901a\u8fc7\u6837\u54c1\u81c2\u548c\u53c2\u8003\u81c2\u7167\u5c04\u5230\u6837\u54c1\u548c\u53c2\u8003\u955c\uff0c\u4e24\u4e2a\u5149\u8def\u4e2d\u7684\u53cd\u5c04\u5149\u5728\u8026\u5408\u5668\u4e2d\u6c47\u5408\uff0c\u800c\u4e24\u81c2\u5149\u7a0b\u5dee\u53ea\u6709\u5728\u4e00\u4e2a\u76f8\u5e72\u957f\u5ea6\u5185\u624d\u80fd\u53d1\u751f\u5e72\u6d89\u4fe1\u53f7\u3002\u540c\u65f6\u7531\u4e8e\u7cfb\u7edf\u7684\u6837\u54c1\u81c2\u662f\u4e00\u4e2a\u5171\u7126\u663e\u5fae\u955c\u7cfb\u7edf\uff0c\u63a2\u6d4b\u5149\u675f\u7126\u70b9\u5904\u8fd4\u56de\u7684\u5149\u675f\u5177\u6709\u6700\u5f3a\u7684\u4fe1\u53f7\uff0c\u53ef\u4ee5\u6392\u9664\u7126\u70b9\u5916\u7684\u6837\u54c1\u6563\u5c04\u5149\u7684\u5f71\u54cd\uff0c\u8fd9\u662fOCT\u53ef\u4ee5\u9ad8\u6027\u80fd\u6210\u50cf\u7684\u539f\u56e0\u4e4b\u4e00\u3002\u628a\u5e72\u6d89\u4fe1\u53f7\u8f93\u51fa\u5230\u63a2\u6d4b\u5668\uff0c\u4fe1\u53f7\u7684\u5f3a\u5ea6\u5bf9\u5e94\u6837\u54c1\u7684\u53cd\u5c04\u5f3a\u5ea6\uff0c\u7ecf\u8fc7\u89e3\u8c03\u7535\u8def\u7684\u5904\u7406\uff0c\u6700\u540e\u7531\u91c7\u96c6\u5361\u91c7\u96c6\u5230\u8ba1\u7b97\u673a\u8fdb\u884c\u7070\u5ea6\u6210\u50cf\u3002
\n\"\"<\/a><\/p>\n

OCT \u6210\u50cf\u7684\u4e3b\u65e8\u5c31\u662f\u8981\u5f97\u5230\u6837\u54c1\u4e0d\u540c\u6df1\u5ea6\u7684\u53cd\u5c04\u7387\u5206\u5e03\u3002\u5982\u679c\u53c2\u8003\u955c\u5904\u7684\u53cd\u5c04\u7387\u4e00\u5b9a\uff0c\u90a3\u4e48\u7531\u4e8e\u6837\u54c1\u7ed3\u6784\u7684\u4e0d\u5747\u5300\u6027\uff0c\u4ece\u6837\u54c1\u4e0d\u540c\u6df1\u5ea6\u6563\u5c04\u56de\u6765\u7684\u5149\u7684\u5f3a\u5ea6\u5c31\u4e0d\u540c\uff0c\u6240\u4ee5\u5f53\u4e24\u81c2\u5149\u76f8\u9047\u65f6\u4ea7\u751f\u7684\u5e72\u6d89\u4fe1\u53f7\u91cc\u5c31\u5e26\u6709\u6837\u54c1\u4e0d\u540c\u6df1\u5ea6\u7684\u5149\u53cd\u5c04\u7387\u4fe1\u606f\u3002\u7531\u5bbd\u5e26\u5149\u6e90\u7684\u4f4e\u76f8\u5e72\u6027\u53ef\u77e5\uff0cOCT\u5e72\u6d89\u4eea\u53ef\u4ee5\u83b7\u5f97\u8f83\u7a84\u76f8\u5e72\u957f\u5ea6\uff0c\u4fdd\u8bc1\u8f74\u5411\u626b\u63cf\u7684\u6210\u50cf\u5206\u8fa8\u7387\u5728\u5fae\u7c73\u7ea7\u3002\u5bf9\u4e8e\u7a84\u5e26\u5149\u6e90\uff0c\u5982\u56fea\u6240\u793a\uff0c\u7531\u4e8e\u5176\u76f8\u5e72\u957f\u5ea6\u5f88\u957f\uff0c\u5728\u76f8\u5f53\u5927\u7684\u5149\u7a0b\u5dee\u8303\u56f4\u5185\u90fd\u80fd\u8f93\u51fa\u5e72\u6d89\u6761\u7eb9\u53d8\u5316\u3002\u8fd9\u6837\u7684\u5e72\u6d89\u6761\u7eb9\u5bf9\u6bd4\u5ea6\u4e0e\u4e24\u81c2\u7684\u5149\u7a0b\u5dee\u53d8\u5316\u51e0\u4e4e\u65e0\u5173\uff0c\u65e0\u6cd5\u786e\u5b9a\u96f6\u7ea7\u6761\u7eb9\u7684\u4f4d\u7f6e\uff0c\u5219\u65e0\u6cd5\u627e\u5230\u7b49\u5149\u7a0b\u70b9\uff0c\u5931\u53bb\u4e86\u7cbe\u786e\u5b9a\u4f4d\u7684\u529f\u80fd\u3002\u800c\u5bf9\u4e8e\u5bbd\u5e26\u5149\u6e90\u800c\u8a00\uff0c\u5982\u56feb\u6240\u793a\uff0c\u53ea\u6709\u5f53\u4e24\u81c2\u7684\u5149\u7a0b\u5dee\u5728\u8fd9\u4e2a\u5f88\u77ed\u7684\u76f8\u5e72\u957f\u5ea6\u4e4b\u5185\u65f6\uff0c\u63a2\u6d4b\u5668\u624d\u80fd\u68c0\u6d4b\u5230\u5e72\u6d89\u6761\u7eb9\u7684\u5bf9\u6bd4\u5ea6\u53d8\u5316\u3002\u800c\u4e14\uff0c\u5728\u5bf9\u6bd4\u5ea6\u6700\u5927\u7684\u5730\u65b9\u5bf9\u5e94\u7740\u7b49\u5149\u7a0b\u70b9\uff0c\u968f\u7740\u5149\u7a0b\u5dee\u7684\u589e\u52a0\uff0c\u5bf9\u6bd4\u5ea6\u8fc5\u901f\u9510\u51cf\uff0c\u56e0\u6b64\u5177\u6709\u5f88\u597d\u7684\u5c42\u6790\u5b9a\u4f4d\u7cbe\u5ea6\u3002\u4e8e\u662f\u53ef\u79fb\u52a8\u53c2\u8003\u81c2\u7684\u53cd\u5c04\u626b\u63cf\u955c\uff0c\u6765\u5bfb\u627e\u53d8\u5316\u540e\u7684\u5e73\u8861\u70b9\uff0c\u901a\u8fc7\u6d4b\u91cf\u53cd\u5c04\u626b\u63cf\u955c\u7684\u53d8\u5316\u524d\u540e\u7684\u4f4d\u79fb\u5373\u53ef\u6d4b\u5f97\u76f8\u5e94\u7684\u5149\u7ea4\u4f20\u611f\u5668\u957f\u5ea6\u7684\u53d8\u5316\u3002
\n\"\"<\/a><\/p>\n

\u7531\u4e8e\u5149\u6e90\u4e3a\u4f4e\u76f8\u5e72\u5bbd\u5e26\u5149\u6e90\uff0c\u6545\u5176\u76f8\u5e72\u957f\u5ea6\u6781\u77ed\u3002\u800c\u53ea\u6709\u5f53\u53c2\u8003\u81c2\u548c\u6d4b\u91cf\u81c2\u5149\u7a0b\u5dee\u5728\u5149\u6e90\u7684\u4e00\u4e2a\u76f8\u5e72\u957f\u5ea6\u4e4b\u5185\u65f6\uff0c\u80cc\u5411\u6563\u5c04\u5149\u548c\u53c2\u8003\u5149\u624d\u4f1a\u4ea7\u751f\u5e72\u6d89\uff0c\u4e14\u5f53\u5149\u7a0b\u5dee\u63a5\u8fd1\u96f6\u65f6\u624d\u5177\u6709\u6700\u5927\u76f8\u5e72\u5f3a\u5ea6\u3002\u56e0\u6b64\uff0c\u968f\u7740\u53c2\u8003\u955c\u7684\u8f74\u5411\u79fb\u52a8\uff0c\u53ef\u9009\u62e9\u6837\u54c1\u4e2d\u4e0e\u4e4b\u5149\u7a0b\u76f8\u7b49\u7684\u5c42\u6765\u8fdb\u884c\u6210\u50cf\uff0c\u800c\u5176\u4ed6\u5c42\u7684\u4fe1\u606f\u5c06\u88ab\u6ee4\u6389\uff0c\u4ece\u800c\u5b9e\u73b0\u4e86\u5c42\u6790\u6210\u50cf\u3002
\n\"\"<\/a><\/p>\n

\u56fe\u4e0a\u6240\u793a\u4e3a\u4e00\u4e2a\u7b80\u5355\u7ec4\u7ec7\u7684\u4e00\u6b21\u7eb5\u5411\u626b\u63cf\u7684\u7ed3\u679c\u3002\u6b64\u6837\u54c1\u7ec4\u7ec7\u7531\u4e24\u5c42\u6784\u6210\uff0c\u6298\u5c04\u7387\u5206\u522b\u4e3an1\u548cn2\uff0c\u4e0e\u7a7a\u6c14\u7684\u6298\u5c04\u7387 n \u4e0d\u540c\u3002\u6837\u54c1\u81c2\u4e2d\uff0c\u5728\u4e24\u79cd\u4e0d\u540c\u6298\u5c04\u7387\u4ecb\u8d28\u7684\u4ea4\u754c\u9762\u5904\u4f1a\u53d1\u751f\u53cd\u5c04\u3002\u5f53\u53c2\u8003\u81c2\u7684\u53cd\u5c04\u955c\u626b\u63cf\u65f6\uff0c\u63a2\u6d4b\u5668\u7684\u8f93\u51fa\u7aef\u53ef\u4ee5\u770b\u5230\u4e24\u4e2a\u5e72\u6d89\u4fe1\u53f7\u3002\u5176\u4e2d\u7b2c\u4e00\u4e2a\u5e72\u6d89\u4fe1\u53f7\u5bf9\u5e94\u7740\u7a7a\u6c14\u4e0e\u7ec4\u7ec7\u5c421\u7684\u4ea4\u754c\u9762\uff0c\u7b2c\u4e8c\u4e2a\u5e72\u6d89\u4fe1\u53f7\u5bf9\u5e94\u7740\u7ec4\u7ec7\u5c421\u4e0e\u7ec4\u7ec7\u5c422\u7684\u4ea4\u754c\u9762\u3002\u5728\u8f7d\u6ce2\u9891\u7387\u5904\u89e3\u8c03\uff0c\u5c31\u53ef\u4ee5\u5f97\u5230\u539f\u59cb\u7684\u5e72\u6d89\u4fe1\u53f7\u7684\u5149\u5f3a\u3002\u901a\u8fc7\u6cbf\u6837\u54c1\u8868\u9762 X \u65b9\u5411\u548c Y \u65b9\u5411\u79fb\u52a8\u6837\u54c1\u81c2\u53ef\u4ee5\u83b7\u5f97\u6837\u54c1\u7684\u4e09\u7ef4\u56fe\u50cf\u3002<\/p>\n

\u9891\u57dfOCT\u6280\u672f
\n\"\"<\/a><\/p>\n

\u9891\u57df OCT \u5728\u8fd1\u5e74\u6765\u6e10\u6e10\u53d6\u4ee3\u4e86\u65f6\u57df OCT\uff0c\u5176\u91cd\u8981\u539f\u56e0\u5728\u4e8e\u5176\u65e0\u9700\u5728\u53c2\u8003\u81c2\u4e2d\u8fdb\u884c\u5149\u7a0b\u626b\u63cf\uff0c\u76f4\u63a5\u4e00\u6b21\u6027\u83b7\u53d6\u7eb5\u5411\u626b\u63cf\u3002\u5982\u6b64\uff0c\u9891\u57dfOCT \u7cfb\u7edf\u7684\u6210\u50cf\u901f\u5ea6\u5c06\u5f97\u5230\u6781\u5927\u63d0\u9ad8\u3002\u65f6\u57df OCT \u91c7\u96c6\u7684\u662f\u968f\u53c2\u8003\u81c2\u5149\u7a0b\u53d8\u5316\u7684\u5f3a\u5ea6\u4fe1\u53f7\uff0c\u5b83\u7684\u6bcf\u4e00\u4e2a\u7eb5\u5411\u626b\u63cf\u65f6\u95f4\u90fd\u7b49\u4e8e\u53c2\u8003\u81c2\u5149\u7a0b\u53d8\u5316\u4e00\u4e2a\u5468\u671f\u7684\u65f6\u95f4\u3002\u9891\u57df OCT \u7684\u53c2\u8003\u81c2\u65e0\u9700\u626b\u63cf\uff0c\u5b83\u4e00\u6b21\u6027\u5730\u91c7\u96c6\u67d0\u4e00\u6a2a\u5411\u4f4d\u7f6e\u7684\u6df1\u5ea6\u65b9\u5411\u7684\u5e72\u6d89\u5149\u8c31\u4fe1\u53f7\uff0c\u4e5f\u5c31\u662f\u9891\u57df\u4fe1\u53f7\u3002\u6df1\u5ea6\u65b9\u5411\u7684\u65f6\u57df\u4fe1\u53f7\u5c31\u7f16\u7801\u5728\u8fd9\u4e2a\u5149\u8c31\u91cc\u3002\u6bcf\u4e00\u4e2a\u7eb5\u5411\u626b\u63cf\u5b9e\u9645\u5c31\u5bf9\u5e94\u4e00\u4e2a\u5e72\u6d89\u5149\u8c31\uff0c\u5bf9\u5149\u8c31\u505a\u5085\u91cc\u53f6\u53d8\u6362\u5373\u53ef\u6062\u590d\u51fa\u65f6\u57df\u4fe1\u53f7\u3002\u9891\u57df OCT \u7701\u53bb\u4e86\u4f20\u7edf\u65f6\u57df OCT \u5f53\u4e2d\u6df1\u5ea6\u626b\u63cf\u7684\u65f6\u95f4\uff0c\u6781\u5927\u63d0\u9ad8\u4e86\u6210\u50cf\u91c7\u96c6\u901f\u5ea6\u3002<\/p>\n

\u83b7\u5f97\u5e72\u6d89\u5149\u8c31\u76ee\u524d\u4e3b\u8981\u6709\u4e24\u79cd\u65b9\u6cd5\uff0c\u4e00\u79cd\u662f\u57fa\u4e8e\u5149\u8c31\u4eea\uff0c\u53e6\u4e00\u79cd\u662f\u57fa\u4e8e\u626b\u9891\u5149\u6e90\u3002\u524d\u8005\u6211\u4eec\u79f0\u4e4b\u4e3a\u5149\u8c31\u9891\u57df OCT(SD-OCT)\uff0c\u540e\u8005\u6211\u4eec\u79f0\u4e4b\u4e3a\u626b\u9891 OCT(SS-OCT)\u3002
\n\"\"<\/a><\/p>\n

SD-OCT\u662f\u901a\u8fc7\u4e00\u4e2a\u57fa\u4e8e\u5149\u6805\u548c\u900f\u955c\u7684\u5149\u8c31\u4eea\uff0c\u5c06\u5e72\u6d89\u4fe1\u53f7\u5206\u5149\u518d\u805a\u7126\u5230\u7ebf\u9635\u7535\u8377\u8026\u5408\u5143\u4ef6harge-Coupled Device\uff0cCCD)\u4e0a\u83b7\u5f97\u5e72\u6d89\u5149\u8c31\u7684\u3002
\n\"\"<\/a><\/p>\n

SS-OCT\u5219\u662f\u901a\u8fc7\u91c7\u7528\u4e00\u4e2a\u8f93\u51fa\u6ce2\u957f\u968f\u65f6\u95f4\u9ad8\u901f\u626b\u63cf\u7684\u626b\u9891\u5149\u6e90\uff0c\u518d\u901a\u8fc7\u63a2\u6d4b\u5668\u8bb0\u5f55\u4e0b\u6bcf\u4e00\u6ce2\u957f\u7684\u4fe1\u53f7\u8fdb\u800c\u5f97\u5230\u5e72\u6d89\u5149\u8c31\u3002<\/p>\n

\u5149\u5b66\u76f8\u5e72\u5c42\u6790\u6280\u672f\u7684\u5e94\u7528<\/p>\n

\u65e9\u671f\u7684OCT\u5927\u591a\u5e94\u7528\u4e8e\u773c\u79d1\uff0c\u56e0\u4e3a\u773c\u775b\u76f8\u5bf9\u6765\u8bf4\u5c5e\u4e8e\u900f\u5149\u6027\u8f83\u597d\u7684\u4ecb\u8d28\u3002\u968f\u7740 OCT \u6280\u672f\u7684\u4e0d\u65ad\u53d1\u5c55\uff0c\u5bf9\u4e8e\u900f\u5149\u6027\u4e0d\u90a3\u4e48\u597d\u3001\u6563\u5c04\u8f83\u5f3a\u7684\u5176\u4ed6\u7ec4\u7ec7\uff0cOCT \u4e5f\u9010\u6e10\u6709\u4e86\u8bb8\u591a\u5e94\u7528\u3002\u5728\u8fc7\u53bb\u5341\u51e0\u5e74\u91cc\uff0cOCT\u4e0e\u5149\u7ea4\u6280\u672f\u548c\u5185\u7aa5\u6280\u672f\u7ed3\u5408\uff0c\u5e94\u7528\u6269\u5c55\u5230\u4e86\u80c3\u80a0\u9053\u3001\u76ae\u80a4\u3001\u80ba\u90e8\u3001\u80be\u810f\u3001\u5fc3\u8840\u7ba1\u7b49\u8bf8\u591a\u9886\u57df\u3002<\/p>\n

\u5728\u773c\u79d1\u65b9\u9762\u7684\u5e94\u7528<\/p>\n

OCT \u6280\u672f\u7684\u7b2c\u4e00\u4e2a\u4e34\u5e8a\u5e94\u7528\u9886\u57df\u5c31\u662f\u773c\u79d1\u5b66\u3002\u7531\u4e8e\u5229\u7528\u4e86\u5bbd\u5e26\u5149\u6e90\u7684\u4f4e\u76f8\u5e72\u6027\uff0cOCT \u5177\u6709\u51fa\u8272\u7684\u5149\u5b66\u5207\u7247\u80fd\u529b\uff0c\u80fd\u591f\u5b9e\u73b0\u5bf9\u6b21\u8868\u9762\u9ad8\u5206\u8fa8\u7387\u7684\u5c42\u6790\u6210\u50cf\uff0c\u5176\u63a2\u6d4b\u6df1\u5ea6\u8fdc\u8d85\u8fc7\u4f20\u7edf\u7684\u5171\u7126\u663e\u5fae\u955c\uff0c\u5c24\u5176\u9002\u5408\u773c\u7ec4\u7ec7\u7684\u6210\u50cf\u7814\u7a76\uff0c\u80fd\u591f\u63d0\u4f9b\u4f20\u7edf\u773c\u79d1\u65e0\u635f\u8bca\u65ad\u6280\u672f\u65e0\u6cd5\u63d0\u4f9b\u7684\u89c6\u7f51\u819c\u65ad\u5c42\u7ed3\u6784\u56fe\u50cf\uff0c\u4e0d\u4ec5\u80fd\u6e05\u6670\u5730\u663e\u793a\u51fa\u89c6\u7f51\u819c\u7684\u7ec6\u5fae\u7ed3\u6784\u53ca\u75c5\u7406\u6539\u53d8\uff0c\u540c\u65f6\u8fd8\u53ef\u4ee5\u8fdb\u884c\u89c2\u5bdf\u5e76\u505a\u51fa\u5b9a\u91cf\u5206\u6790\uff0c\u5176\u5728\u773c\u79d1\u8bca\u65ad\u65b9\u9762\u7684\u7814\u7a76\u662f OCT \u751f\u7269\u533b\u5b66\u5e94\u7528\u53d1\u5c55\u7684\u91cd\u70b9\u65b9\u5411\u4e4b\u4e00\uff0c\u5bf9\u773c\u79d1\u75be\u75c5\u8bca\u65ad\u505a\u51fa\u91cd\u5927\u8d21\u732e\uff0c\u76ee\u524d\u5df2\u6210\u4e3a\u89c6\u7f51\u819c\u75be\u75c5\u548c\u9752\u5149\u773c\u5f3a\u6709\u529b\u7684\u8bca\u65ad\u5de5\u5177\u3002<\/p>\n

\u968f\u7740 OCT \u6027\u80fd\u7684\u63d0\u9ad8\uff0c\u53ef\u4ee5\u9884\u6d4b OCT \u5bf9\u773c\u79d1\u5c06\u4ea7\u751f\u66f4\u52a0\u6df1\u8fdc\u7684\u5f71\u54cd\uff0c\u4ece\u800c\u53ef\u4ee5\u63d0\u9ad8\u75be\u75c5\u65e9\u671f\u8bca\u65ad\u7684\u7075\u654f\u5ea6\u548c\u7279\u5f02\u6027\uff0c\u6539\u53d8\u76d1\u6d4b\u75be\u75c5\u8fdb\u5c55\u7684\u80fd\u529b\u3002OCT \u5bf9\u4e8e\u7406\u89e3\u89c6\u7f51\u819c\u7684\u7ed3\u6784\u548c\u529f\u80fd\uff0c\u89e3\u91ca\u89c6\u7f51\u819c\u75be\u75c5\u7684\u53d1\u75c5\u673a\u7406\uff0c\u786e\u5b9a\u65b0\u578b\u6cbb\u7597\u65b9\u6848\uff0c\u76d1\u6d4b\u75be\u75c5\u6cbb\u7597\u6548\u679c\u7b49\u65b9\u9762\u8d77\u7740\u8d8a\u6765\u8d8a\u91cd\u8981\u7684\u4f5c\u7528\u3002\u76ee\u524d\u5728\u4e34\u5e8a\u4e0a OCT \u4e3b\u8981\u7528\u4e8e\u9752\u5149\u773c\u3001\u9ec4\u6591\u75c5\u53d8\u3001\u73bb\u7483\u4f53\u89c6\u7f51\u819c\u75be\u75c5\u3001\u89c6\u7f51\u819c\u4e0b\u65b0\u751f\u8840\u7ba1\u7684\u65e9\u671f\u8bca\u65ad\u53ca\u672f\u540e\u968f\u8bca\u3002<\/p>\n

\u5728\u76ae\u80a4\u79d1\u65b9\u9762\u7684\u5e94\u7528<\/p>\n

OCT \u6280\u672f\u5df2\u7ecf\u8fbe\u5230\u4eba\u4f53\u76ae\u80a4\u6210\u50cf\u7684\u76ee\u7684\u3002\u9ad8\u5206\u8fa8\u7387\u7684 OCT \u80fd\u68c0\u6d4b\u5230\u4eba\u4f53\u5065\u5eb7\u76ae\u80a4\u7684\u8868\u76ae\u5c42\u3001\u771f\u76ae\u5c42\u3001\u9644\u5c5e\u5668\u548c\u8840\u7ba1\u3002Welzel\u7b49\u5b9e\u73b0\u4e86 OCT \u7cfb\u7edf\u7684\u4eba\u4f53\u76ae\u80a4\u6210\u50cf\uff0c\u6210\u50cf\u7cfb\u7edf\u4e2d\u6ce2\u957f\u4e3a 830nm\uff0c\u6df1\u5ea6\u5206\u8fa8\u7387\u4e3a 15\u03bcm\uff0c\u63a2\u6d4b\u6df1\u5ea6\u4e3a 0.5~1.5mm\uff0c\u6210\u50cf\u65f6\u95f4\u4e3a10~40s\u3002Wang \u7b49\u8fd8\u53ef\u4ee5\u63cf\u7ed8\u51fa\u8f74\u5411\u5206\u8fa8\u7387<10\u03bcm\u7684\u5728\u4f53\u5c0f\u9f20\u76ae\u80a4\u548c\u4eba\u4f53\u80c3\u80a0\u9053\u7684 OCT\u6210\u50cf\uff0c\u5c06\u7518\u6cb9\u548c\u4e19\u4e8c\u9187\u6d82\u4e8e\u5c0f\u9f20\u76ae\u80a4\u8868\u9762 OCT \u6210\u50cf\uff0c\u53ef\u89c1\u8868\u76ae\u3001\u8868\u76ae\u57fa\u5e95\u5c42\uff0c\u771f\u76ae\u4e73\u5934\u5c42\u3001\u771f\u76ae\u7f51\u7edc\u5c42\uff0c\u76ae\u4e0b\u7ec4\u7ec7\uff0c\u7b4b\u819c\uff0c\u808c\u8089\u548c\u6bdb\u56ca\u3002<\/p>\n

OCT \u53ef\u4ee5\u7528\u4e8e\u635f\u4f24\u4fee\u590d\u76d1\u6d4b\u3002Yeh \u7b49\u7528 OCT\u3001\u591a\u5149\u5b50\u663e\u5fae\u955c(Multiphoton microscope\uff0cMPM)\u5728\u76ae\u80a4\u7ec4\u7ec7\u4eff\u771f\u6a21\u578b\u4e2d\u76d1\u6d4b\u6fc0\u5149\u70ed\u635f\u4f24\u548c\u968f\u540e\u7684\u635f\u4f24\u4fee\u590d\u3002\u79bb\u4f53\u7684\u76ae\u80a4\u7ec4\u7ec7\u4eff\u771f\u6a21\u578b\u7531\u542b\u67091\u578b\u80f6\u539f\u86cb\u767d\u3001\u7ea4\u7ef4\u7ec6\u80de\u7684\u771f\u76ae\u548c\u4e0d\u540c\u89d2\u86cb\u767d\u9176\u7684\u8868\u76ae\u7ec4\u6210\u3002\u975e\u4fb5\u5165\u6027\u5149\u6210\u50cf\u6280\u672f\u88ab\u7528\u4f5c\u968f\u65f6\u95f4\u53d8\u5316\u7684\u57fa\u8d28\u635f\u4f24\u548c\u4fee\u590d\u7684\u7cfb\u5217\u6d4b\u91cf\uff0c\u5e76\u4e0e\u7ec4\u7ec7\u75c5\u7406\u5b66\u68c0\u67e5\u7ed3\u679c\u5bf9\u6bd4\u3002<\/p>\n

\u5728\u5fc3\u8840\u7ba1\u7cfb\u7edf\u7684\u5e94\u7528<\/p>\n

OCT \u4f5c\u4e3a\u975e\u4fb5\u5165\u6027\u68c0\u6d4b\u6280\u672f\u7528\u4e8e\u6d3b\u4f53\u8840\u6db2\u6210\u50cf\uff0c\u5728\u751f\u7269\u533b\u5b66\u7814\u7a76\u548c\u4e34\u5e8a\u8bca\u65ad\u4e2d\u5177\u6709\u5f88\u5927\u7684\u4ef7\u503c\u3002\u5149\u5b66\u591a\u666e\u52d2\u5c42\u6790\u6210\u50cf(Optical Doppler tomography\uff0cODT)\u662f\u5c06\u6fc0\u5149\u591a\u666e\u52d2\u6d41\u91cf\u8ba1\u4e0e OCT\u76f8\u7ed3\u5408\uff0c\u4e5f\u79f0\u4f5c\u5f69\u8272\u591a\u666e\u52d2\u76f8\u5e72\u5c42\u6790\u6210\u50cf(Color Doppler optical coherence tomography\uff0cCDOCT)\uff0c\u53ef\u8fbe\u5230\u4eba\u4f53\u8840\u6d41\u7684\u9ad8\u5206\u8fa8\u7387\u6210\u50cf\u548c\u5b9e\u65f6\u68c0\u6d4b\u3002Chen \u7b49\u7528 ODT \u83b7\u5f97\u4e86\u5728\u4f53\u9e21\u80da\u7ed2\u6bdb\u819c\u548c\u556e\u9f7f\u7c7b\u52a8\u7269\u80a0\u7cfb\u819c\u7684\u6d3b\u4f53\u8840\u6d41\u5c42\u6790\u901f\u5ea6\u6210\u50cf\uff0c\u5e76\u76d1\u6d4b\u5bf9\u4e8e\u8840\u7ba1\u6d3b\u6027\u836f\u7269\u7684\u5e72\u9884\u548c\u5149\u52a8\u529b\u5b66\u6cbb\u7597\u540e\u8840\u6d41\u52a8\u529b\u5b66\u7684\u6539\u53d8\u53ca\u8840\u7ba1\u7ed3\u6784\u7684\u53d8\u5316\u3002<\/p>\n

\u5728\u8de8\u79d1\u624b\u672f\u9886\u57df\u7684\u5e94\u7528<\/p>\n

\u5728\u8de8\u79d1\u624b\u672f\u65b9\u9762\uff0cOCT\u53ef\u5728\u53bb\u9664\u80bf\u7624\u7684\u624b\u672f\u8fc7\u7a0b\u4e2d\u5206\u6790\u6709\u65e0\u764c\u7ec6\u80de\u3002\u4e00\u822c\u800c\u8a00\uff0c\u5916\u79d1\u533b\u751f\u53d6\u51fa\u80bf\u7624\u5468\u56f4\u7ec4\u7ec7\u65f6\uff0c\u603b\u662f\u5e0c\u671b\u80fd\u6e05\u9664\u6240\u6709\u7684\u764c\u7ec6\u80de\u3002\u800c\u88ab\u6e05\u9664\u7684\u80bf\u7624\u53ca\u5468\u56f4\u7684\u7ec4\u7ec7\u4f1a\u9001\u81f3\u75c5\u7406\u5b9e\u9a8c\u5ba4\u8fdb\u884c\u4e00\u5468\u7684\u5206\u6790\uff0c\u4ee5\u505a\u51fa\u624b\u672f\u540e\u7684\u4e66\u9762\u62a5\u544a\u3002\u7531\u4e8eOCT\u5f71\u50cf\u5728\u7ec4\u7ec7\u5b66\/\u75c5\u7406\u5b66\u5e94\u7528\u5747\u4e3a\u76f8\u540c\u7684\u5206\u8fa8\u7387\uff0c\u56e0\u6b64\u624b\u672f\u5ba4\u4e2d\u7684OCT\u7cfb\u7edf\u80fd\u591f\u8ba9\u5916\u79d1\u533b\u751f\u5728\u624b\u672f\u8fc7\u7a0b\u4e2d\u7cbe\u786e\u5730\u77e5\u9053\u9700\u8981\u6e05\u9664\u591a\u5c11\u7ec4\u7ec7\uff0c\u540c\u65f6\u7559\u4e0b\u591a\u5c11\u5b89\u5168\u8fb9\u7f18\u90e8\u4efd\uff0c\u91c7\u7528\u5982\u6b64\u7684\u505a\u6cd5\u4fbf\u4e0d\u4f1a\u9519\u8bef\u53bb\u9664\u672a\u611f\u67d3\u764c\u75c7\u7684\u7ec4\u7ec7\uff0c\u56e0\u800c\u7701\u5374\u540e\u7eed\u624b\u672f\u7684\u8d39\u7528\u53ca\u75db\u82e6\u3002OCT\u6280\u672f\u80fd\u591f\u8ba9\u533b\u751f\u4ee5\u7ec4\u7ec7\u5b66\u7684\u5206\u8fa8\u7387\u6c34\u5e73\uff0c\u5b9e\u65f6\u770b\u89c1\u5f71\u50cf\uff0c\u4ee5\u4fbf\u5728\u7b2c\u4e00\u6b21\u8fdb\u884c\u53bb\u9664\u80bf\u7624\u7684\u5916\u79d1\u624b\u672f\u65f6\u505a\u51fa\u66f4\u597d\u7684\u51b3\u5b9a\u3002<\/p>\n

\u65e5\u540e\u4f1a\u6709\u66f4\u591a\u91c7\u7528OCT\u6280\u672f\u7684\u533b\u7597\u5e94\u7528\u3002\u4f8b\u5982\uff0cOCT\u80fd\u591f\u642d\u914d\u7a7f\u523a\u5207\u7247\u5207\u9664\u65e9\u671f\u9636\u6bb5\u7684\u5c0f\u80bf\u7624\u3002\u5bf9\u4e8e\u7f79\u60a3\u4e73\u764c\u7684\u75c5\u60a3\uff0cOCT\u53ef\u642d\u914d\u89c6\u89c9\u53ca\u201c\u667a\u80fd\u201d\u4fe1\u53f7\u5904\u7406\u6280\u672f\uff0c\u5f15\u5bfc\u7ec6\u9488\u63d2\u5165\u7cbe\u786e\u7684\u80bf\u7624\u4f4d\u7f6e\uff0c\u4ee5\u67e5\u660e\u7591\u4f3c\u611f\u67d3\u7684\u7ec4\u7ec7\uff0c\u5c3d\u53ef\u80fd\u51cf\u5c11\u624b\u672f\u7684\u4fb5\u5165\u6027\u3002\u5bf9\u4e8e\u5fc3\u8840\u7ba1\u75be\u75c5\u60a3\u8005\uff0cOCT\u53ef\u642d\u914d\u6781\u5c0f\u578b\u5bfc\u7ba1\u652f\u67b6\uff0c\u66f4\u51c6\u786e\u5730\u627e\u51fa\u8840\u7ba1\u5185\u652f\u67b6\u6216\u68c0\u67e5\u6591\u5757\u6c89\u79ef\u3002\u5728\u8fd9\u4e9b\u7c7b\u578b\u7684\u5e94\u7528\u4e2d\uff0c\u5148\u8fdb\u7684\u6570\u5b57\u4fe1\u53f7\u5904\u7406\u6280\u672f\u4e0d\u4ec5\u80fd\u591f\u8fbe\u5230\u7edd\u4f73\u7684\u5f71\u50cf\u753b\u8d28\uff0c\u800c\u4e14\u80fd\u591f\u8fdb\u884c\u7ec4\u7ec7\u5206\u7c7b\u3002<\/p>\n

\u975e\u533b\u5b66\u9886\u57df\u7684\u5e94\u7528<\/p>\n

OCT \u7814\u7a76\u7684\u6700\u521d\u76ee\u7684\u662f\u4e3a\u751f\u7269\u533b\u5b66\u7684\u5c42\u6790\u6210\u50cf\uff0c\u5e76\u4e14\u533b\u5b66\u5e94\u7528\u4ecd\u7136\u7ee7\u7eed\u5360\u4e3b\u5bfc\u5730\u4f4d\u3002\u9664\u4e86\u5728\u533b\u5b66\u9886\u57df\u7684\u5e94\u7528\uff0c\u968f\u7740 OCT \u6280\u672f\u7684\u53d1\u5c55\uff0cOCT \u6280\u672f\u6b63\u5728\u5411\u5176\u4ed6\u9886\u57df\u63a8\u8fdb\uff0c\u7279\u522b\u662f\u5de5\u4e1a\u6d4b\u91cf\u9886\u57df\uff0c\u5982\u4f4d\u79fb\u4f20\u611f\u5668\u3001\u8584\u5e95\u7247\u7684\u539a\u5ea6\u6d4b\u91cf\u4ee5\u53ca\u5176\u4ed6\u53ef\u4ee5\u8f6c\u6362\u6210\u4f4d\u79fb\u7684\u88ab\u6d4b\u7269\u7684\u6d4b\u91cf\u3002<\/p>\n

\u6700\u8fd1\uff0c\u4f4e\u76f8\u5e72\u6280\u672f\u5df2\u4f5c\u4e3a\u9ad8\u5bc6\u5ea6\u6570\u636e\u5b58\u50a8\u7684\u5173\u952e\u6280\u672f\u3002OCT \u6280\u672f\u8fd8\u53ef\u7528\u4e8e\u6d4b\u91cf\u9ad8\u6563\u5c04\u805a\u5408\u7269\u5206\u5b50\u7684\u6b8b\u4f59\u5b54\u9699\u3001\u7ea4\u7ef4\u6784\u9020\u548c\u7ed3\u6784\u7684\u5b8c\u6574\u6027\u3002\u8fd8\u53ef\u4ee5\u7528\u4e8e\u6d4b\u91cf\u6750\u6599\u7684\u9540\u5c42\u3002OCT \u6280\u672f\u8fd8\u80fd\u7528\u4e8e\u6750\u6599\u79d1\u5b66\uff0cJ.P.Dunkers \u7b49\u4eba\u4f7f\u7528OCT \u6280\u672f\u5bf9\u590d\u5408\u6750\u6599\u8fdb\u884c\u4e86\u65e0\u635f\u4f24\u7684\u68c0\u6d4b\u3002 M.Bashkansky \u7b49\u4eba\u5229\u7528 OCT \u7cfb\u7edf\u5bf9\u9676\u74f7\u6750\u6599\u8fdb\u884c\u4e86\u68c0\u6d4b\uff0c\u62d3\u5c55\u4e86 OCT \u6280\u672f\u7684\u5e94\u7528\u8303\u56f4\u3002S.R.Chinn \u7b49\u8fd8\u5bf9 OCT \u5728\u9ad8\u5bc6\u5ea6\u6570\u636e\u5b58\u50a8\u4e2d\u7684\u5e94\u7528\u8fdb\u884c\u4e86\u7814\u7a76\uff0c\u5b9e\u73b0\u591a\u5c42\u5149\u5b66\u5b58\u50a8\u548c\u9ad8\u63a2\u6d4b\u7075\u654f\u5ea6\u3002<\/p>\n

OCT\u6280\u672f\u7684\u672a\u6765\u53d1\u5c55\u8d8b\u52bf<\/p>\n

\u672a\u6765OCT\u7684\u53d1\u5c55\u8d8b\u52bf\u5927\u81f4\u53ef\u4ee5\u8ba4\u4e3a\u662f\u4ece\u5355\u7eaf\u7ed3\u6784\u6210\u50cfOCT\u5411\u529f\u80fd\u548c\u7ed3\u6784\u7efc\u5408\u6210\u50cf\u7684OCT\u53d1\u5c55\u3002\u901a\u5e38\u751f\u7269\u7ec4\u7ec7\u5728\u4ea7\u751f\u75c5\u53d8\u4e4b\u524d\u5176\u529f\u80fd\u53c2\u6570\u5c31\u5df2\u5f00\u59cb\u53d1\u751f\u53d8\u5316\uff0c\u56e0\u6b64\uff0c\u529f\u80fd\u53c2\u6570\u5bf9\u75be\u75c5\u65e9\u671f\u8bca\u65ad\u662f\u975e\u5e38\u6709\u7528\u7684\u3002\u8fd9\u4e9b\u529f\u80fd\u53c2\u6570\u901a\u5e38\u5305\u542b\u8840\u6d41\u901f\u5ea6\u3001\u542b\u6c27\u538b\u3001\u7ec4\u7ec7\u7ed3\u6784\u53d8\u5316\u3001\u53cc\u6298\u5c04\u6027\u8d28\u7b49\uff0c\u529f\u80fd\u578bOCT\u901a\u8fc7\u63a2\u6d4b\u8fd9\u4e9b\u53d8\u5316\u8fdb\u884c\u529f\u80fd\u6210\u50cf\u63d0\u4f9b\u66f4\u591a\u4fe1\u606f\u3002\u8fd1\u5e74\u6765\u5f97\u5230\u5feb\u901f\u53d1\u5c55\u7684\u529f\u80fd\u578b\u7684OCT\u6280\u672f\u5305\u62ec\uff1a\u591a\u666e\u52d2OCT\u3001\u504f\u632f\u5149\u654f\u611fOCT\u3001\u5149\u8c31\u578bOCT\u548c\u53cc\u5149\u7ebfOCT\u3002<\/p>\n

\u5149\u5b66\u76f8\u5e72\u5c42\u6790\u6210\u50cf\u4f5c\u4e3a\u4e00\u79cd\u65b0\u9896\u7684\u6210\u50cf\u6280\u672f\uff0c\u80fd\u5bf9\u6d3b\u4f53\u7ec4\u7ec7\u5185\u90e8\u5fae\u5c0f\u7ed3\u6784\u8fdb\u884c\u5b9e\u65f6\u3001\u5728\u4f53\u3001\u9ad8\u5206\u8fa8\u7387\u65ad\u5c42\u6210\u50cf\uff0c\u4e0e\u4f20\u7edf\u6210\u50cf\u8bca\u65ad\u65b9\u6cd5\u76f8\u6bd4\uff0c\u663e\u793a\u51fa\u6781\u5927\u7684\u4f18\u8d8a\u6027\uff0c\u5728\u533b\u5b66\u75be\u75c5\u8bca\u65ad\u4e2d\u5177\u6709\u5f88\u5927\u7684\u6f5c\u529b<\/p>\n","protected":false},"excerpt":{"rendered":"

\u5149\u5b66\u76f8\u5e72\u5c42\u6790(Optical Coherence Tomography\uff0c\u7b80\u79f0 OCT)\u662f 20 \u4e16\u7eaa 90 \u5e74 […]<\/p>\n","protected":false},"author":1,"featured_media":333,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15,16],"tags":[],"class_list":["post-310","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-15","category-16"],"_links":{"self":[{"href":"https:\/\/www.wayln.com\/index.php?rest_route=\/wp\/v2\/posts\/310","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wayln.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wayln.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wayln.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wayln.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=310"}],"version-history":[{"count":1,"href":"https:\/\/www.wayln.com\/index.php?rest_route=\/wp\/v2\/posts\/310\/revisions"}],"predecessor-version":[{"id":311,"href":"https:\/\/www.wayln.com\/index.php?rest_route=\/wp\/v2\/posts\/310\/revisions\/311"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.wayln.com\/index.php?rest_route=\/wp\/v2\/media\/333"}],"wp:attachment":[{"href":"https:\/\/www.wayln.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=310"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wayln.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=310"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wayln.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=310"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}